A Case Study: Neuraxpharm & 3DforScience
Visualizing Advanced MS Therapy Mechanisms with Clarity and Impact
Neuraxpharm, Europe’s specialist in central nervous system (CNS) therapies, partnered with 3DforScience to develop a high-impact animation explaining the mode of action of BRIUMVI® (ublituximab) — a glycoengineered anti-CD20 antibody bringing new hope to people living with multiple sclerosis (MS).
The Vision:
Explaining Complex Science to Empower Treatment Decisions
Over 2.8 million people worldwide live with MS, a neuroinflammatory disease without a known cure. While B cells were once overlooked in MS pathology, they are now understood as central contributors to myelin destruction and neuroinflammation. Neuraxpharm aimed to translate this updated understanding and BRIUMVI’s unique mode of action into an engaging visual narrative, making the science accessible for clinicians, patients, and stakeholders.
2.8 million
People worldwide live with multiple sclerosis.
25–30x
Greater ADCC potential compared to other anti-CD20 antibodies.
96%
CD19+ B cell depletion within 24 hours of first dose in ULTIMATE I/II trials.
A Tailored Story for CNS Specialists
The animation walks the viewer through MS progression: from B cell-driven myelin damage to the precise targeting action of BRIUMVI®. It visualizes how ublituximab’s glycoengineering enhances its affinity for FcγRIIIa receptors, increasing NK cell-mediated cytolysis (ADCC) while maintaining complement-dependent cytolysis (CDC). This dual mechanism achieves effective B cell depletion at lower doses and with shorter infusion times, delivering both efficacy and efficiency.
A Tailored Story for CNS Specialists
The animation walks the viewer through MS progression: from B cell-driven myelin damage to the precise targeting action of BRIUMVI®. It visualizes how ublituximab’s glycoengineering enhances its affinity for FcγRIIIa receptors, increasing NK cell-mediated cytolysis (ADCC) while maintaining complement-dependent cytolysis (CDC). This dual mechanism achieves effective B cell depletion at lower doses and with shorter infusion times, delivering both efficacy and efficiency.
KNOW-HOW: Scientific Accuracy in Every Frame
Our team collaborated closely with Neuraxpharm’s medical experts to ensure molecular details were represented accurately. From antibody design and receptor binding to B cell depletion graphs, every frame balanced scientific precision with clear, intuitive visuals. Dynamic sequences emphasized how BRIUMVI® controls inflammation and supports better patient outcomes.
From concept to visualization
Starting from Neuraxpharm’s core script and scientific data, we developed layered visuals: real-life inspired key visuals, detailed antibody interactions, and dynamic charts showing trial results. Smooth transitions tied the mechanism to patient benefit, reinforcing BRIUMVI®’s promise.
Solutions applied
Hand-made conceptual styling
Modelling of illustrations and designs
3D scientific animations and recreation
Our Approach to Creating an Impactful Experience
Beyond explaining BRIUMVI®’s science, the animation connects with the audience emotionally, reminding viewers of the daily lives impacted by MS. Visual storytelling bridges the gap between molecular immunology and real-world relief, making the science memorable and persuasive.
Our Approach to Creating an Impactful Experience
Beyond explaining BRIUMVI®’s science, the animation connects with the audience emotionally, reminding viewers of the daily lives impacted by MS. Visual storytelling bridges the gap between molecular immunology and real-world relief, making the science memorable and persuasive.
Our workflow:
From concept to delivery
The project integrated script development, storyboard creation, 3D antibody modeling, animation of cellular interactions, and brand-aligned final editing. Close review with Neuraxpharm’s teams ensured the content was medically accurate and visually aligned with the BRIUMVI® and Neuraxpharm brand identity..
The final outcome
The final animation is now a cornerstone in Neuraxpharm’s medical communication toolkit. It supports HCP education, conference presentations, and digital engagement — demonstrating how BRIUMVI® offers new hope in MS care by combining scientific innovation with patient-centered efficiency.
“Neuraxpharm entrusted us with visualizing a complex therapy and its patient benefit. Together, we turned advanced immunology into a story of efficacy, efficiency, and hope for millions living with MS.”
Would you like to explore areas of cooperation?
We are proud partners of top healthcare Agencies globally. If you’re interested in a potential collaboration, let’s talk! Together, we can make great things happen!
Send us a message today.
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