A Case Study: 4TEEN4 & 3DforScience
Visualizing Procizumab’s Mechanism to Redefine Critical Care
4TEEN4, a biotechnology innovator focused on critical care solutions, collaborated with 3DforScience to develop a high-impact mechanism-of-action animation for Procizumab, a monoclonal antibody designed to neutralize the harmful enzyme DPP3 released during acute cellular injury. The goal was to translate complex circulatory biology into an accessible visual narrative that supports scientific communication, investor engagement, and clinical dialogue.
The Vision:
Clarifying a Critical Care Innovation Through Visual Science
When tissues die as a result of acute events like myocardial infarctions or shock from sepsis, burns, or trauma, intracellular enzymes such as DPP3 are released into the bloodstream. Once in circulation, DPP3 degrades angiotensin, a key regulator of blood pressure and organ perfusion, impairing circulatory function and leading to widespread organ dysfunction. 4TEEN4’s vision with Procizumab is to demonstrate how targeted neutralization of DPP3 can preserve angiotensin levels, restore systemic circulation, and protect critical organs, offering new possibilities in acute care.
31% decrease in perfusion
Visualized in the early animation stages to show the physiological impact of angiotensin degradation on organs.
>90% enzyme neutralization
Represented in animation to demonstrate Procizumab’s rapid binding and inhibition of DPP3 in preclinical models.
3 shock scenarios visualized
Myocardial infarction, sepsis, and trauma — each depicted to convey broad mechanism relevance.
A Tailored Story for Critical Care Audiences
The animation begins with a semi-transparent human anatomy illustrating a heart under attack, showing necrotic cells releasing DPP3 into the bloodstream. Through realistic 3D vascular animation, angiotensin molecules are shown breaking down, leading to compromised perfusion in the heart, kidneys, and lungs; a visceral depiction of circulatory collapse.
A Tailored Story for Critical Care Audiences
The animation begins with a semi-transparent human anatomy illustrating a heart under attack, showing necrotic cells releasing DPP3 into the bloodstream. Through realistic 3D vascular animation, angiotensin molecules are shown breaking down, leading to compromised perfusion in the heart, kidneys, and lungs; a visceral depiction of circulatory collapse.
KNOW-HOW: Scientific Accuracy in Every Frame
Our team worked closely with 4TEEN4’s scientific advisors to ensure physiological events and antibody interactions were modeled with precision. From detailed molecular representations of DPP3 inhibition to organ-level perfusion changes, each visual element was crafted to reflect current understanding of circulatory pathophysiology. This balance of scientific fidelity and visual clarity allows complex mechanisms to be intuitively communicated without oversimplification.
From concept to visualization
We began with a deep analysis of 4TEEN4’s scientific narrative, identifying key events in acute circulatory disruption and rescue. Early storyboards outlined the visual arc, from tissue injury to systemic recovery, and were refined to match the pacing and tone of the 70-second script. 3D modeling brought cellular enzymes, angiotensin molecules, and antibodies to life, while whole-body visualizations established context for organ function. Seamless visual transitions tied molecular action to physiological restoration, reinforcing Procizumab’s potential impact on critical care.
Solutions applied
Hand-made conceptual styling
Modelling of illustrations and designs
3D scientific animations and recreation
Our Approach to Creating an Impactful Experience
Procizumab’s story is not only about molecules, it’s about life preserved. The visual narrative was designed to resonate with both scientific and emotional impact, showing how rapid enzyme neutralization translates to organ protection. By bridging molecular pharmacology with whole-body physiology, the animation supports clinical education, investor discussions, and scientific outreach, making the innovation both understandable and memorable.
Our Approach to Creating an Impactful Experience
Procizumab’s story is not only about molecules, it’s about life preserved. The visual narrative was designed to resonate with both scientific and emotional impact, showing how rapid enzyme neutralization translates to organ protection. By bridging molecular pharmacology with whole-body physiology, the animation supports clinical education, investor discussions, and scientific outreach, making the innovation both understandable and memorable.
Our workflow:
From concept to delivery
The project encompassed scientific script refinement, storyboard development, 3D modeling of molecular and anatomical systems, animation, and final post-production. Close collaboration with 4TEEN4 teams ensured that each scientific claim was validated, contextually represented, and aligned with the brand’s vision of redefining critical care.
The final outcome
The Procizumab mechanism-of-action animation now stands as a core asset for 4TEEN4, helping communicate the science to clinicians, potential partners, and broader stakeholders. By translating complex circulatory biology into clear, impactful visuals, the video strengthens understanding of DPP3 inhibition and underscores Procizumab’s promise as a transformative intervention in acute care settings.
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