Asp-1929 3D cell animation and mechanism of action for Rakuten Medical
“Beautiful mechanism of action video for our lead candidates Asp-1929 and IRDye 700DX made by a fantastic team. It was a pleasure working with 3DforScience team, we’d love to work with them in the future and would highly recommend their work to others.”
Associate Director , Phd
First of all, we analyze the information, graphics and schemes given by the client. Once the creative team has understood the project begins to develop and improve the graphics. a deeper research about the real structures of proteins, molecules and cells is necessary to develop 3d cell animation and models.
In this case, we researched for the tridimensional structure of cetuximab, available in the Protein Data Bank (https://www.rcsb.org/), also how cetuximab is attached to the photoactivatable payload (IRDye 700DX).
We process each raw 3D cell animation model from the PDB, giving it shape, texture and a unique aesthetic appearance. in this case, we represent the real structure of cetuximab and for the IRDye 7000DX, we develope that 3D structure to be able to show in each visualization a representation of the anticancer substance.
Once the complex reaches the tumour we create a cancer medical animation and visualization of the cell surface showing the EGFR and the antibody approaching and binding it.
Furthermore, the subsequent activation of immune cells will contribute to the process such as NK and tumour-specific cytotoxic T cells.
Moreover, it was important for the client to highlight the natural origin of the use of Sappi Symbio in automotive design. Thus, we animate the car, driving through the forest to display the reduced environmental impact this biocomposite has.