3D Mode of action Fairence®- A novel tranexamic acid creme for melasma

7 Minutes




Hyphens Pharma focuses on the sales and marketing of specialty pharmaceutical products in selected ASEAN countries through exclusive distributorship or licensing and supply agreements with brand principals mainly from Europe and the United States.

Scientifically developed and owned by Hyphens Pharma, their dermatology products are marketed under the  TDF Derma Formula®  brand.

Established first in USA and later Singapore in 1994, TDF Derma Formula is the pioneer in alpha-hydroxy acids (AHA) glycolic acid formulations and a trusted brand in the field of dermatology.

Their mission at TDF is to improve skin health and raise self-esteem of those with problematic skin. They provide science-based solutions with superior quality and proven efficacy across different skin types and skin conditions such as acne, hyperpigmentation, photoaging and aging skin. TDF skincare products deliver visible results, putting you one step closer to greater skin confidence.

Today, TDF is an established prescriptive skincare brand with a strong reputation amongst medical professionals in many countries – Singapore, Malaysia, Indonesia and Hong Kong to name a few.


From 3DforScience, we produced a 3D animation to explain the mechanism of Action (MOA) of  Fairence® T-Complex. This product is scientifically designed with the Xcelarev® technology, a patented delivery system. Incorporated with 3 key ingredients, Tranexamic acid, Niacinamide and Lactobionic acid, Xcelarev® enhances skin lightening effect to combat dark spots.

Throught this 3D animation video, we explain first of all the disorder called Melasma, which is a common, therapeutically challenging, and universally relapsing disorder of hyperpigmentation that is most often observed in women and individuals with Fitzpatrick Skin Types III through VI.

We also explain that various treatments have been trialed, including topical hypopigmentation agents, laser or light therapies, and chemical peels. Hyphens Pharma Pte Ltd came up with TDF® Fairence® T-Complex, a scientifically designed pigment lightening cream powered by Xcelarev® Technology, a UK patented delivery system that delivers the Triactive ingredients deeper into the skin.

firenance 3d animation video

Incorporated with 3 key ingredients – 2% Tranexamic acid, Niacinamide and Lactobionic acid which works synergistically to reduce intensity of dark spots and pigmented skin effectively. Tranexamic acid helps in reduction of melanin production, improving overall skin tone and also reduces vascular factors that contribute to melasma. Niacinamide slows down the transfer of melanin to the skin surface thus reducing uneven pigmentation. Lastly, Lactobionic Acid, a polyhydroxy acid (PHA) with antioxidant property increases cellular turnover, reducing the appearance of the dark spots.

All this process can be observed in detail thanks to the 3D animation video that we have developed in 3DforScience, where each element that participates in this cellular process is observed. Fairence ® has been clinically tested hypoallergenic and is well tolerated thus can be used for long term. Recommended to apply with the TDF PA+++ UVA/UVB SPF 50+ Sunscreen.

firenance t-complex 3d video


Is a scientific communication company specialized in digital content for the pharma and biotech industries. Our passionate creative team, works alongside an in-house scientific team to provide cutting-edge medical animations, scientific illustrations, virtual reality, etc.

Our extensive experience within the field ensures all the content we produce is scientifically accurate, innovate, engaging, and pitched at the right level for the target audience. Wold you like to bring your scientific messaging to life? Contact us. We would love to help you create something unique.

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